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Blog: Medizone (MZEI)

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Medizone International, Inc.(OTCBB: MZEI)

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Dear Member,

The following Chairman’s Message was just released by Edwin
Marshall, the CEO and Chairman of the Board of Medizone
International:

John Pentony
Publisher, StockGuru

Chairman’s Message

Shareholder Update, February 8, 2010 

Let me start by wishing everyone an excellent 2010.  Medizone
reached milestones during 2009 relative to the AsepticSure™
development program that sets the pulse not only for a very successful
2010, but I believe has laid the foundation for achieving full
commercialization in the area of hospital sterilization and critical
infrastructure clean up in addition to the exceedingly strong
likelihood of contributing greatly in the area of bio-terrorism counter
measures. These are two distinct avenues of revenue production, both
with an increasingly high likelihood of commercial
success.  

I would like to acknowledge the tremendous level of leadership skill
that has been demonstrated by Dr. Michael Shannon, one of Medizone’s
Board Members and our Director of Medical Affairs. Michael has been
instrumental in the building of a research and development team that may be
un-paralleled for a company of Medizone’s size. The accomplishments
this group of esteemed men has achieved is remarkable.  To repeatedly
and predictably be able to achieve 6 log (99.9999%) sterilization standards
of bactericidal kill across the full spectrum of bacteria we have worked
with in open space settings is unprecedented.  It is amazing to me
that our development team has reached these previously unachievable levels
of scientific success in only one year.  A year ago initial
conversations were in the works with those who are now our key people about
the possibility of developing equipment to help rid hospitals of HAIs, and
the science we thought it would take to reach that goal.  We had no
equipment, nor a laboratory, but together we did bring a wealth of
experience, knowledge, ideas and a team of incredibly talented bright
people that were destined to find a synergy, a magic, in working together
on a unique project. Today, we have three highly successful laboratory
trials behind us and a full scale hospital mock up trial in progress, which
has already demonstrated our equipment will deliver as promised in the
field, and two new patent applications filed for commercial
protection.  What a difference one year has made! 
Remarkable!

In recapping our work in 2009 that set the agenda for moving forward
from where we are today, let me start by broadly reviewing the steps that
have brought us to this present stage.  In the first round of trials,
working just with ozone as the primary agent, we achieved in the area of 3
log (99.9%) to 4 log (99.99%) of bactericidal reductions on average. 
For the second round of trials our “formula” was tweaked a
little bit, and the results improved by a log on average, putting us
solidly in the 4 log to 5 log range. With an impressive amount of data
logging achieved, and following a thorough search of the patent literature
by two patent firms, our first patent application was filed for
AsepticSure™ July 6, 2009 titled “Healthcare Facility
Disinfecting System” US application 61/223,219. That filing made
three distinct and unique claims based not only on inventive engineering
design and protocols, but backed up with solid scientific evidence that was
demonstrated to be repeatable. This patent protects the Company’s
basic disinfectant procedure and protocol, involving the use of
ozone-containing atmosphere, and the apparatus used for implementing
it.

For the third round of trials recently completed, an additional
technology was integrated that catapulted AsepticSure™ to the
accepted sterilization standard of 6 logs or greater (99.9999% bactericidal
kill.)  This result is phenomenal in that Medizone is the only company
in the world known to have reached this standard, and it has done so using
a product that is portable, affordable and is now proving capable of full
room sterilization with a turn around time of 2 hours or less for re-use,
while not damaging electronics and other built in infrastructure within the
room. 

The actual measured numbers of bactericidal reduction from the
completed third round of laboratory trials when compared to the larger
samples were >6.5 log for C difficile, >7 log
for MRSA, 7 log for E-coli, 6.6 Log
for VRE, 7 log for Pseudomonas aeruginous and
> 7 log for Bacillus subtilis.  Given this
unprecedented scientific data and the protocols compiled as part of the
patent applications, in combination with the uniqueness of the invention
itself, gives Medizone every confidence that our patent protection will
stand firm and strong and protect the commercial rights of shareholders
well into the future as Medizone transitions to a revenue producing
company. 

A second patent filing for AsepticSure™ was announced on January
20, 2010 titled “Disinfecting Process and Apparatus” US
application 61/295,851. This protects improvements in the Company’s
basic procedure and protocol achieved by combining it with another
procedure, resulting in a significant increase in disinfecting capabilities
demonstrated during the third round of laboratory trials against a wide
variety of bacteria and on a range of different surfaces commonly found in
healthcare and other essential facilities.  Both patent applications
currently afford international protection for this technology, and can be
expanded into full international patent applications, in countries of the
Company’s choice, in the months ahead. 

On February 4th 2010 Medizone announced a successful progression
to full room scale testing, achieving total eradication (>6 logs) with
all bacteria tested to date (MRSA, VRE and E coli)
on every single run.  Additional testing now underway with the
remaining causative agents of HAIs, are expected to replicate the results
achieved in our small laboratory test unit with the remaining bacteria,
just as these early mock trial results have already proven.  It was
stated in the February 4 th press release, “It now seems
certain that AsepticSure™ will deliver as promised.” It is a
simple statement, but absolutely true!   

2010 is clearly starting out as great year for Medizone International.
I believe it will prove to be a year of dramatic transition, accomplishment
and reward.  The goal of becoming a significant revenue producing
company is progressing toward reality with an historic scientific product
that we believe is strongly protected intellectually. When the mock trials
currently underway are completed, we expect to then be positioned to move
into hospital beta testing at sites in both the United States and
Canada.  The final step is then expected to be sales and partnering
with major corporate partners already fully imbedded in the hospital sector
for additional manufacturing, sales and service support.  As results
are produced in the field in the form of cleaner hospitals and a reduced
incident of HAIs, it is assured that product demand will be strong. The
potential for Medizone International to now develop into a solid, revenue
producing growth company for many years to come is significant.  I
believe the year 2010 will prove to be historic in our company’s
history. 

To be able to greatly reduce human suffering, save thousands if not
tens of thousands of lives and be able to significantly reduce hospital
operating costs all in one broad stroke called AsepticSure™, will
truly prove to be a significant achievement in the history of science and
medicine.  I believe Medizone International is now firmly on the
threshold of that achievement.  Stand by, I promise you there will be
more news to come in the months ahead! 

Yours truly,

Edwin G. Marshall

Chairman of the Board

Chief Executive Officer 

This Chairman’s message contains certain forward
looking statements that involve substantial risks and uncertainties,
including, but not limited to, the results of ongoing clinical studies,
economic conditions, product and technology development, production
efficiencies, product demand, competitive products, competitive
environment, successful testing and government regulatory issues.
Additional risks are identified in the company’s filings made with the
Securities and Exchange Commission. 

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Medizone International, Inc.(OTCBB: MZEI)

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